Abstract: Through the detailed investigation of the potash deposit in Seitani county, Vientiane city, Laos, the methods of gravity survey, integrated logging, sampling and analysis have been selected for geophysical survey, and good results have been obtained. Gravity survey delineated 2 types of 18 favorable target areas for mineralization, comprehensive logging was used to determine the exact location and thickness of orebody, sampling was used to calculate the density of orebody, and laboratory analysis was used to calculate the grade of orebody. The application results of this method in prospecting in this area and the characteristics of potash ore body are presented, which provides important basic parameters and basis for the estimation of potash ore body resources (storage).