Abstract: Cenozoic domes separated by detachments and formed during the India-Eurasian collision, are commonly distributed in the southern Pamir. The core complex of these domes are made up of high-grade metamorphic rocks and granite. The granite mainly formed during the Late Mesozoic and minor of them formed during the Cenozoic. The granite samples gathered along the detachments and from the granite comprising the bulk Alichur dome are measured by on the LA-MC-ICP U-Pb zircon dating. The formation times of the granite are 19.30±0.36 Ma and 111.7±0.8 Ma. Hf-isotopic characteristics of zircon demonstrate the granite formed by partial melting of crust. The Cenozoic granite is probably closely associated with the structural decompression caused by the extensional decollement of the domes.