Abstract: The Luanchuan mining area is located at the southern edge of the North China Craton, which is rich in mineral resources and has produced a number of large-sized and super-large porphyry-silica type molybdenum and tungsten deposits. There are frequent magmatic activities in Late Mesozoic, forming several ore-bearing granite bodies and porphyry rock strains, and the controlling factors of their mineralization differences and potentials are still unclear. In this paper, we take the Mo-rich granite body of Nannihu and the ore-poor granite body of Shibaogou in the Luanchuan mining concentration area as the research objects, and based on zircon U-Pb dating and Hf-O isotope study, we reveal the age of their diagenesis and metallogeny, magma source area, and metallogeny indication significance. The zircon U-Pb ages of the Shibaogou rock and the Nannihu rock are (147.5±2.2) Ma and (139.5±1.8) Ma, respectively, and both are the products of Yanshan-age magmatism. The zircon εHf(t) values of the Shibaogou body range from −27.40～−14.51, and the two-stage mode age T_DM2 values range from 2.15～2.93 Ga, with δ¹⁸O values of 5.42‰ to 6.77‰. The zircon εHf(t) values of the Nannihu body range from −16.84～−8.04, with second-stage mode age T_DM2 values ranging from 1.70～2.26 Ga and δ¹⁸O values of 5.88‰～8.27‰. The zircon U-Pb ages and Hf-O isotope results indicate that the source area of the Shibaogou ore-poor magma originated from partial melting of the thickened lower crust of the Qinling orogenic belt in the context of localized extensional downstretching of post-collisional orogeny; and that the Mo-rich porphyry magma of the Nannihu is characterized by crust-mantle mixing.