Abstract: The magmatic Cu-Ni sulfide deposits produced in the northern orogenic belt of Xinjiang are important Cu-Ni resource bases in northwest China. In the process of geophysical exploration of magmatic Cu-Ni sulfide deposits, comprehensive geophysical prospecting indicators of High magnetism, High weight, High polarizability, Low resistivity (Three High with One low) were summarized and established, which guided the discovery and evaluation of a number of medium and large deposits. With the continuous improvement of geological work in the mineralization zone, the exploration direction of magmatic Cu-Ni sulfide deposits has gradually shifted to concealed and deep orebodies, and the difficulty of exploration has significantly increased. Based on the geological characteristics of magmatic Cu-Ni sulfide deposits in northern Xinjiang, the author analyzed the current status and existing problems of geophysical exploration modes in the area in recent years, and explored the application prospects of multiple new geophysical technologies, providing new ideas for achieving deep and refined detection targets of magmatic Cu-Ni sulfide deposits.