Abstract: The relationship between the widely developed porphyritic granites and iron mineralization in the Wengjile skarn-type iron deposit, located in the Tashkurgan area of the West Kunlun orogenic belt, remains unclear. This study investigates two types of porphyritic granites in the mining area: grayish-white (containing grayish-white K-feldspar phenocrysts) and light flesh-red (containing light flesh-red K-feldspar phenocrysts). Through petrography, zircon U-Pb geochronology, Hf isotope analysis, whole-rock geochemistry, and oxygen fugacity calculations, we elucidate their petrogenesis, source characteristics, tectonic setting, and metallogenic significance. LA-ICP-MS zircon U-Pb dating yields consistent ages of ～13.6 Ma for both granite types, indicating that they are products of Miocene magmatism. The Wengjile granites exhibit adakitic affinities, characterized by high Sr (773.32×10⁻⁶–1437.81×10⁻⁶), low Y (3.12×10⁻⁶–18.07×10⁻⁶) and Yb (0.25×10⁻⁶–1.16×10⁻⁶), and high Sr/Y ratios (61.05–460.98). Their low MgO (0.50%–0.77%), Ni (2.50×10⁻⁶–5.45×10⁻⁶) and Cr (8.39×10⁻⁶–13.87×10⁻⁶) contents, enriched zircon Hf isotopic compositions (ε_Hf(t) values range from –6.3 to –3.4), and insignificant Eu anomalies suggest that the Wengjile granites were derived from partial melting of thickened ancient eclogite-facies lower crust. Combined with previous studies, the generation of the Wengjile granites was controlled by the post-collisional setting of the India-Eurasia plate collision, wherein localized delamination of the lithospheric mantle, triggered by continued crustal thickening in the Pamir region, was an important factor promoting partial melting of the thickened ancient lower crust. The Wengjile granites exhibit relatively high oxygen fugacity (ΔFMQ values range from 0.19 to 2.47). In addition, the granites are generally enriched in biotite, and the positive correlation between zircon Ce/Sm and Yb/Gd ratios indicates fractional crystallization of amphibole, suggesting a water-rich magma. Comprehensive analysis suggests that magma source characteristics, relatively high oxygen fugacity, and water-rich conditions are key factors controlling the Wengjile skarn-type iron mineralization. The Tashkurgan area, where adakitic rocks are widely developed, shows considerable exploration potential, with magmatic oxygen fugacity and water content serving as important prospecting indicators.