Abstract: Northwest China is not only vast in territory and rich in energy resources, but also has frequent geological disasters and heavy geological survey tasks. For a long time, the regional geophysical work in Northwest China has supported the exploration and research of regional geology, energy resources and geological disasters. This paper systematically combs the current situation of work and summarizes the progress of regional gravity, aeromagnetism, deep exploration and comprehensive research in Northwest China, and puts forward the prospect of the next work according to the characteristics of the new period.