Abstract: In order to ensure the quality of the second grade highway from Xi'an to Ankang and find out the influence of slide in Zhujiawan region on the highway engineering, the geological and seismic geophysical exploration methods were used to explore earth surface and deep geological condition in this slide region.And on the basis of the two methods, the geological situation, origin of the slides and slope stability are mainly focused on studying and analysis in the region.In addition, some satisfactory conclusions are finally drawn by analysis data and information, which are surveyed and collected on the spot.Some conclusion and suggestion will play an important role in the engineering practice in the future.