Abstract: As one of the most important minralization zones for nonferrous, ferrous and precious metals in China, the eatern Tianshan orogen straddles between the Kazakstan and the Tarimplates.The orogen has experienced formation of the Pre-Sinian basement, evolution of the paleo-Asian ocean during Sinian-Devonian, post collision orogeny during Carboniferous-early Permian and intracontinental orogeny from late Permian to now.The major ore-forming period is late Paleozoic and mineralization has been complicated.The major ore deposits in the eastern Tianshan are: porphyry copper and volcanic Cu, Mo and Au formed in an island-arc setting distributed in the northern part of the eastern Tianshan; volcanic and skarn Au, Cu, Ni and Ag in a rifting environment occurring in the central part; strata-bound and hydrothermal Pb, Zn and Ag deposit in the central-southern part and Cu, Ni and Au deposits in an extentional setting in the southern Kuruktag and Beishan.It is suggested that the eastern Tianshan has great potential for Cu, Ni and Mo deposits and 28 areas have been selected as target for further exploration.