Abstract: According to research achievement of mineral exploration in depth of Xiaoqinling golddeposit region and prospecting practice for Chen'er gold ore deposit, it concluded that Xiaoqinling gold deposit region is another super-large ore cluster region, which have superior exploration condition and potential in depth. It has large favorable districts for exploration located in depth or surrounding of known deposits. Some exploration targets should be paid attention to, such as extending, lateral currence, and wedge out of main orebody. There is possiblity to find structure altered rock type gold deposit in depth of quartz vein type gold deposit. On the base of strengthening geology synthetical study and understanding metallogenic regularity, the effective methods for exploration in depth includes geology, geophysics, and geochemistry comprehensive new techniques, and so on. It can forecast deep enriched section of orebody by using the geochemical axis zoned model, and prove by drill project in hole.