Abstract: The Makmal large-scale gold deposit, located in Middle Tianshan orogenic belt of Kyrgyzstan, belongs to the contact metasomatic type gold deposit of intermediate-acidic intrusions. The intermediate-acidic intrusive rocks are widely distributed in Xinjiang, where many gold deposits or occurrences are found developed within intermediate-acidic intrusions or their outer contact zone. Thus, the mineralization conditions and prospecting potential of this type of gold deposit are satisfied in Xinjiang, and three middle-scale gold deposits (such as Duonalasayi deposit) have been found there recently. However, this type of gold deposit is less in origin and small in scale. In this paper, the geological characteristics of Makmal large-scale gold deposit have been summarized to provide some help for prospecting this type of gold deposits in Xinjiang.