Abstract: Mengxi copper deposit is regarded as one of the best metallogenic prospects copper deposits in Xinjiang east junggar.In this paper, element enrichment and depletion regularity and primary anomaly zoning sequence were studied.The results show that there exist positive anomalies of ore-forming and associated elements and mineralizer elements and negative anomalies of Nb in the ore deposit.The space distribution range of negative anomaly formed by depleted elements than the positive anomaly formed by enriched elements is bigger, and the whole deposit occurs in a depletion halo formed by the negative anomalies.The major indicator elements of the Mengxi copper deposit not only have obvious elements concentration zoning, but also have element zoning characteristics.Primary anomaly zoning sequence is established: (Au), Bi , Cd-Sb , Ag, Hg-S-Mo, Cu, (Au)。The result obtained by the authors provides a basis for the prospecting work in the depth and the periphery of the ore district.