Abstract: In this paper, the Taxkorgan area of West kunlun Mountains has been selected as a study object, the WorldView-2 remote sensing images have been used as major data source to make standard image map and as the adopting methods to enhance the image for protruding the information of ore-controlling factors and mineralization, and the interpretation of remote sensing for mineral resources has been carried out.After using ASTER and WorldView-2 data to carry out alteration anomaly information extraction, 11 remote sensing prospecting targets have been circled on through implementing a right amount of field investigation verification, including 5 of A-class, 3 of B-class and 3 of C-class, which are used as the basis for deploying mineral resources survey project and exploration and evaluation of mineral resources.Therefore, the high precision remote sensing technology is worth to be further promoted and applied in the same or similar area of West Kunlun, because it can realize the rapid breakthrough of ore prospecting work in the mineral geological survey.