Abstract: Moshigou manganese mining area in Qinghai is a platform basin sedimentary manganese carbonate deposit newly discovered in the south slope of East Kunlun in recent years, which mainly occurs at the top of the carbonate formation of Wanbaogou group in meso Neoproterozoic. Manganese bearing rock series and manganese orebody are characterized by large thickness, stable extension, simple lithologic combination, low overall grade but large reserves. They are one of the few manganese ore exploration bases with good prospects in Qinghai Province. According to the latest exploration results of Moshigou manganese mining area, it is inferred that the genesis of the deposit is closely related to hot water sedimentation from the aspects of metallogenic geological background, geological characteristics of the mining area, thick dolomite carbonaceous slate manganese bearing rock series, layered densely distributed manganese ore bodies, ore quality characteristics, main and trace element characteristics, etc., and the metallogenic model of hot water sedimentary manganese ore in Moshigou area is preliminarily explored. Through comprehensive analysis, the prospecting potential of Moshigou manganese mining area is preliminarily evaluated, so as to provide prospecting reference for similar sedimentary manganese ore exploration.